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Adenosine-5'-triphosphate (ATP) is the medium for the supply and demand of energy in living cell systems. However, the effective qualities of ATP have not been fully clarified to date, that is, a complete molecular theory explaining the transfer of chemical energy to physical strength in living organisms has not been established. The aim of this research field is investigate the related fundamental themes covering both the fields of material science and life science. With water, the environmental foundation supporting the existence of all living organisms, the fundamental guideline here is to open a new interdisciplinary research field, one that is not constricted by the existing concepts, and aim for a new energy theory explaining the fundamental molecular structure of intercellular energy transfer, soundly based on structural and functional theory. In order to accomplish this task, the fusion of separate research fields, leading to the development of a new methodology concept and the fostering of a new generation of research scientists are essential. Along with the existing scheduled research, we intend to vitalize public appeals for unique research opportunities across a wide range of research fields, and promote the systematization of these projects while maintaining a close relationship between the various theoretical and experimental research efforts.
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The theory of energy in living organisms clearly shows a dynamic, continuous
supply and demand of energy. The molecule that functions as the vehicle
for this supply and demand of energy is adenosine-5'-triphosphate (ATP).
A large amount of free energy is created (called ATP energy) during the
process of ATP hydrolysis where ATP is converted into ADP and inorganic
phosphoric acid Pi or the opposite reaction where ATP is created. Especially
surprising is the fact that even now, more than 80 years after the discovery
of ATP, and about 60 years after it was proposed to be the main molecule
involved in inter-cellular energy transfer, no molecular theory on the
source of ATP energy exists verified by rigorous scientific experiments.
As if that is not deplorable enough, even in fields such as biochemistry
and biophysics, where there is a direct relationship with energy theory,
across the entire field of life science the subject has been treated as
if a theory has been established stating that the source of ATP energy
is the instability of the structure of the ATP molecule itself. It may
be considered that the main reason for this worrisome situation is the
rarefied quality of the substantialism-like awareness of the interaction
between water, the environmental mother of all living organisms on earth
and bio molecular particles. This situation is in stark contrast to the
established theory on the function of the complementary bonding of hydrogen
molecules between with the bases that form DNA molecules in the replication
and transcription of information.
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In order to achieve the aims of this research field, it is essential to
develop new methodologies through the "Fusion" of a wide range
of different fields of research. To that end, we are promoting close cooperation
and the systemization of fundamental research, the formation of new theories
and experimental verification research (single molecule measurements, precise
measurements of reaction heat, and the analysis of hydration conditions
through studies on the dielectric dispersion spectroscopy) through gathering
together research experts in various fields, such as solution chemistry,
statistical biophysics, and biochemistry. It is expected that the promotion
of fusion research covering these various subjects, such as single molecule
measurements, solution chemistry and thermal measurements, and an integrated,
organic approach covering both structural and functional aspects, will
lead to a new, higher level energy theory. |
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